Table 2.
Univariate and multivariate analysis for overall survival (OS) and event free survival (EFS) in patients with diffuse large B-cell lymphoma (N = 81)*
| Univariate |
Multivariate |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OS |
P | EFS |
P | OS |
P | EFS |
P | |||||
| hazard ratio | 95% confidence interval | hazard ratio | 95% confidence interval | hazard ratio | 95% confidence interval | hazard ratio | 95% confidence interval | |||||
| RDW (%) |
7.146 |
2.758-18.517 |
<0.001 |
5.026 |
2.273-11.113 |
<0.001 |
3.654 |
1.128-11.836 |
0.031 |
2.611 |
1.012-6.739 |
0.047 |
| Age (year) |
1.048 |
1.008-1.09 |
0.019 |
1.051 |
1.014-1.089 |
0.006 |
- |
- |
0.761 |
- |
- |
0.305 |
| Sex (male) |
2.737 |
1.051-5.652 |
0.038 |
- |
- |
0.076 |
- |
- |
0.14 |
- |
- |
- |
| ECOG PS (≥2) |
6.202 |
2.518-15.278 |
<0.001 |
4.195 |
1.868-9.421 |
0.001 |
3.497 |
1.265-9.669 |
0.016 |
- |
- |
0.091 |
| IPI (>2) |
7.761 |
2.613-23.049 |
<0.001 |
5.387 |
2.261-12.835 |
<0.001 |
- |
- |
0.374 |
- |
- |
0.116 |
| LDH (>241 U/L) |
4.689 |
1.727-12.73 |
0.002 |
3.491 |
1.524-7.994 |
0.003 |
- |
- |
0.556 |
- |
- |
0.409 |
| Clinical stage AA (III and IV) | 6.623 | 1.546-28.378 | 0.011 | 3.097 | 1.170-8.203 | 0.023 | - | - | 0.488 | - | - | 0.974 |
*RDW – red blood cell distribution width; ECOG PS – Eastern Cooperative Oncology Group performance status; IPI – International prognostic index; LDH – lactate dehydrogenase; AA – Ann Arbor.