Figure 3.

Classification of inversions according to their overlap with gene regions. The 1092 inversions reported in InvFEST [39] are classified into three main categories: (i) Intergenic, which do not disrupt any genic sequence, even though they might invert complete genes; (ii) Intronic, which are completely included within the intron of a gene; and (iii) Break genes, which are inversions that disrupt genes, either at their ends or inverting any internal exons. Colors indicate the status of inversions as shown in the legend, and illustrate that more than half of inversions that disrupt genic sequences might be false positives. (A colour version of this figure is available online at: http://bfg.oxfordjournals.org)