Table 3.

Numbers of patients reporting nasal symptoms over the course of immunotherapy

Treatment	Nasal symptoms
	Children			Adolescents
	Year	Symptoms		Year	Symptoms
		Yes	No		Yes	No
Grass pollen	0	458	30	0	348	25
	1	436	41	1	318	50***
	2	313	69****	2	210	75****
	3	172	72****	3	115	73***
Tree pollen	0	470	19	0	321	19
	1	428	52****	1	295	41***
	2	306	65**	2	203	69****
	3	169	53	3	104	68***
Tree/Grass	0	158	16	0	119	8
	1	145	24	1	111	9
	2	101	39***	2	82	20**
	3	67	29	3	40	30***
Mites	0	361	107	0	273	59
	1	304	154****	1	242	81*
	2	230	197****	2	205	107*
	3	137	164*	3	126	101*
Mixed	0	53	3	0	58	3
	1	49	6	1	53	8
	2	40	9	2	46	12
	3	26	11	3	35	9

Statistical comparison by chi-square test of distribution for each year with preceding year (*p < 0.05, **p < 0.01, ***p < 0.005, ****p < 0.001).