. Author manuscript; available in PMC: 2015 Sep 21.

Published in final edited form as: Oncogene. 2011 Oct 3;31(21):2680–2690. doi: 10.1038/onc.2011.441

Table 1. Summery of genomic alterations.

Genomic alterations in tumor DNA was examined by aCGH using the ADM-2 algorithm and the Agilent CGH Analytics V3.4 software. The range of alterations is shown for each tumor type. To ascertain common regions of genomic alterations, probe signals were averaged by genotype and deletions or gains determined as described above. The data are represented as % probes gained or lost.

Tumor genotype		Range		Averaged Signal

	n	Gains	losses	Gains	losses
p53^+/+	5	0.1–10.5	0.1–0.3	0.2	0.4
p53^+/−	6	0.1–21.0	0.2–1.4	0.2	0.7
p53^−/−	7	0.1–12.0	0.1–13.0	5.7	0.5
p53^R172H/−	10	5.8–30.1	0.4–6.2	11.2	1.7
p53^R172H/+	10	0.1–45.7	0.1–13.8	17	1.1