Table 2.
Baseline demographics and disease characteristics
| All patients (N = 17) | |
|---|---|
| Sex, n (%) | |
| Female | 9 (53) |
| Age (years) | |
| Median | 30 |
| Minimum, maximum | 18, 66 |
| GCTB disease type, n (%) | |
| Primary resectable | 2 (12) |
| Primary unresectable | 5 (29) |
| Recurrent resectable | 2 (12) |
| Recurrent unresectable | 8 (47) |
| Location of target lesion, n (%) | |
| Sacrum | 5 (29) |
| Lung | 3 (18) |
| Tibia | 2 (12) |
| Femur | 1 (6) |
| Humerus | 1 (6) |
| Lumbar vertebrae | 1 (6) |
| Pelvic bone | 1 (6) |
| Pleura | 1 (6) |
| Radius | 1 (6) |
| Skull | 1 (6) |
| Previous treatment of GCTB, n (%) | |
| Chemotherapy | 1 (6) |
| Radiation | 0 (0) |
| Surgeries | 8 (47) |
| Bisphosphonate (oral) | 1 (6) |
| Bisphosphonate (i.v.) | 5 (29) |
| Interferon | 0 (0) |
N is the number of patients who received ≥1 dose of denosumab.