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. 2015 Jul 28;26(10):2161–2168. doi: 10.1093/annonc/mdv330

Table 1.

Distribution of patient characteristics by year of diagnosis using three time periods

Variable Level 2002–2003
N = 1206
2004–2006
N = 1945
2007–2009
N = 1867
P-value
Age at diagnosis Mean 77.3 77.4 77.3 0.87
Race
White 981 (81.3%) 1513 (77.8%) 1494 (80.0%) 0.01
Black 146 (12.1%) 269 (13.8%) 206 (11.0%)
Others 79 (6.6%) 163 (8.4%) 167 (8.9%)
Comorbidity score
0 828 (68.7%) 1294 (66.5%) 1207 (64.6%) 0.02
1 252 (20.9%) 382 (19.6%) 406 (21.7%)
2+ 126 (10.4%) 269 (13.8%) 254 (13.6%)
Tumor size (mm)
≤20 125 (10.4%) 325 (16.7%) 304 (16.3%) <0.0001
>20, ≤50 335 (27.8%) 589 (30.3%) 627 (33.6%)
>50 237 (19.7%) 418 (21.5%) 412 (22.1%)
Unknown 509 (42.2%) 613 (31.5%) 524 (28.1%)
Region of patient's residence
Midwest 161 (13.3%) 270 (13.9%) 262 (14.0%) 0.95
Northeast 325 (26.9%) 506 (26.0%) 474 (25.4%)
South 291 (24.1%) 493 (25.3%) 472 (25.3%)
West 429 (35.6%) 676 (34.8%) 659 (35.3%)
Urban/rural residence
Big metro 676 (56.1%) 1076 (55.3%) 1036 (55.5%) 0.23
Metro 362 (30.0%) 556 (28.6%) 516 (27.6%)
Other 168 (13.9%) 313 (16.1%) 315 (16.9%)
ER status
Unknown 459 (38.1%) 486 (25.0%) 382 (20.5%) <0.0001
Positive 557 (46.2%) 1093 (56.2%) 1136 (60.8%)
Negative 190 (15.8%) 366 (18.8%) 349 (18.7%)
PR status
Unknown 490 (40.6%) 520 (26.7%) 408 (21.8%) <0.0001
Positive 405 (33.6%) 830 (42.7%) 871 (46.7%)
Negative 311 (25.8%) 595 (30.6%) 588 (31.5%)
Hormone receptor
Negative 175 (14.5%) 350 (18.0%) 327 (17.5%) <0.0001
Positive 570 (47.3%) 1108 (57.0%) 1156 (61.9%)
Unknown 461 (38.2%) 487 (25.0%) 384 (20.6%)
Chemotherapy
No 723 (60.0%) 1228 (63.1%) 1170 (62.7%) 0.17
Yes 483 (40.0%) 717 (36.9%) 697 (37.3%)
Radiation therapy
No 808 (67.0%) 1293 (66.5%) 1261 (67.5%) 0.78
Yes 398 (33.0%) 652 (33.5%) 606 (32.5%)
Surgery
No 720 (59.7%) 1214 (62.4%) 1272 (68.1%) <0.001
Yes 486 (40.3%) 731 (37.6%) 595 (31.9%)

Values are given as n (%).

ER, estrogen receptor; PR, progesterone receptor.