Table 1B.
p-Values for Repeated Measures Analysis to Determine the First Day with Significant Increase in Viral Load (HIV-1CHO77 Virus)
| Assay | Day 7 (vs. day 4) | Day 11 (vs. day 4) | Day 14 (vs. day 4) |
|---|---|---|---|
| Assay 1 (T, DNA) | 0.698 | 0.053 | 0.060 |
| Assay 2 (T, DNA) | 0.245 | 0.176 | 0.048 |
| Integration (T, DNA) | 0.847 | 0.002 | 0.002 |
| Assay 3 (T, RNA) | 0.277 | 0.059 | 0.178 |
| Assay 4 (T, RNA) | 0.731 | 0.067 | 0.040 |
| Assay 3 (S, RNA) | 0.251 | 0.348 | 0.432 |
| Assay 4 (S, RNA) | 0.635 | 0.800 | 0.577 |
| HIV-1 p24 (S, HIV-1 p24) | 0.349 | 0.044 | 0.012 |
Samples are compared to reference day = 4 because that is the first day at which we have a sufficient number of samples measured for each assay for comparison.
Real-time PCR assays and HIV-1 p24 ELISA were performed to measure levels of HIV-1 nucleic acid and antigen in tissues (T) and supernatant fluids (S) after infection with HIV-1CH077.