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. 2015 Mar 31;212(8):1250–1260. doi: 10.1093/infdis/jiv204

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Published by Oxford University Press on behalf of the Infectious Diseases Society of America 2015. This work is written by (a) US Government employee(s) and is in the public domain in the US.

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Figure 2. — Individual subject changes in overall and organ-specific quantitative ¹⁸F-fluorodeoxyglucose positron emission tomographic (PET) abnormalities between flare and remission. Comparison of organ-specific maximal standardized uptake value (SUV_max) between active disease and remission in patients with paired PET scans (n = 16 but n = 15 for spleen) showed statistically significant reductions in metabolic activity of lymph nodes, spleen, salivary glands, and bone marrow; changes were most marked for nodes and spleen. For lymph nodes, this difference remained significant with partial volume correction (PVC) (median decrease in PVC SUV_max, 2.1; P = .004 [not shown]). Note that the vertical axis scales differ.