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. 2015 Apr 15;212(8):1322–1331. doi: 10.1093/infdis/jiv217

Figure 1.

Figure 1.

Up-regulation of the inflammatory response biofunction in Rwandan adults during mild malaria compared with day 30 of convalescence. The Ingenuity Pathway Analysis inflammatory response canonical pathway was significantly up-regulated (P = 1.25 × 10−8 –3.48 × 10−2) during infection and was generated from the differentially abundant transcripts at the time of malaria infection compared with day 30 of convalescence (P < .001; false discovery rate, ≤0.006). Pink denotes up-regulation; blue, down-regulation. Abbreviations: IFN, interferon; IgG, immunoglobulin G; IL1RL1, interleukin 1 receptor–like 1; IL5RA, interleukin 5 receptor, alpha subunit; IL-6; interleukin 6; IL-12, interleukin 12; IL-12B, interleukin 12B; IL-13, interleukin 13; MAPK, mitogen-activated protein kinase; MHC, major histocompatibility complex; MMP9, matrix metalloproteinase 9; PD-L1, programmed death ligand 1; TGF, transforming growth factor; TLR1, Toll-like receptor 1.