Table 4. Correlation of serum miR-130a levels with clinically important biochemical parameters.
Data are presented as coefficients of correlation. Statistically significant correlations are marked in bold and italics.
| miR-130a correlation | Test cohort | Validation cohort | ||
|---|---|---|---|---|
| rS | MM | EM | MM | EM |
| Monoclonal Ig (g/l) | - 0.201 | - 0.217 | 0.259 | 0.067 |
| Hemoglobin (g/l) | 0.270 | 0.201 | - 0.268 | 0.267 |
| Thrombocytes (count x109) | 0.245 | 0.426 | 0.131 | - 0.120 |
| Calcium (mmol/l) | - 0.025 | - 0.006 | 0.033 | 0.183 |
| Albumin (g/l) | 0.170 | 0.380 | - 0.096 | 0.236 |
| Creatinine (μmol/l) | - 0.129 | 0.050 | 0.150 | - 0.123 |
| β2-microglobulin (mg/l) | - 0.216 | - 0.185 | 0.368 | - 0.315 |
| Lactate dehydrogenase (μkat/l) | 0.048 | - 0.082 | 0.045 | - 0.010 |
| C-reactive protein (mg/l) | - 0.176 | - 0.322 | 0.007 | - 0.069 |
| Plasma cells infiltration of bone marrow (%) | 0.046 | - 0.416 | - 0.075 | - 0.325 |