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. 2015 Sep 21;10(9):e0138780. doi: 10.1371/journal.pone.0138780

Fig 4. C10 displaces the RNA from RRM1-2/RNA complex.

Fig 4

(A) Overlay of free RRM1-2 (blue) and RRM1-2/RNA (red). (B) Overlay of free RRM1-2 (blue) and RRM1-2/RNA/C10. (C) Zoom-in region of (A). (D) Zoom-in region of (B). When RNA binds to RRM1-2, many peaks disappeared as indicated in the cycle and arrow. The peaks come back once adding C10 to RRM1-2/RNA complex, indicating that C10 does block the RRM1-2/RNA interaction.