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. 2015 Sep 21;10(9):e0138215. doi: 10.1371/journal.pone.0138215

Fig 5. Different effects of mGluR antagonists on TBS-induced shifts in EGABA in juvenile and neonatal rat hippocampal neurons.

Fig 5

In panel A, MPEP and LY367385 did not block TBS-induced negative shifts in EGABA as observed in control condition (reported in [2,3] in 9–12 day old rat hippocampal neurons while the co-application of these two antagonists blocked this negative shift in EGABA. In panel B, either MPEP or LY367385 is able to inhibit TBS-induced positive shifts in EGABA in 3–5 day old rat hippocampal neurons. EGLU didn’t block the TBS-induced shifts in both 9–12 and 3–5 day old rat hippocampal neurons. The n in brackets refers to the number of neurons. *P<0.05.