Table 3. Top three pathways identified by SPIA.
| Pathway | P NDE | FDRNDE | P PERT | FDRPERT | P G | FDRG |
|---|---|---|---|---|---|---|
| Acute myeloid leukemia | 1.40E-3 | 0.11 | 0.11 | 1.00 | 1.54E-3 | 6.25E-2 |
| Insulin signaling pathway | 6.09E-3 | 0.19 | 0.79 | 1.00 | 3.05E-2 | 0.55 |
| mTOR signaling pathway | 7.11E-3 | 0.19 | 0.95 | 1.00 | 4.06E-2 | 0.55 |
Notes: SPIA: Signaling Pathway Impact Analysis. P NDE is the P value of over-representation evidence, P PERT is the P value of perturbation evidenceand PG is the P value of combined over-representation evidence and perturbation evidence.