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. 2015 Aug 24;112(37):11612–11617. doi: 10.1073/pnas.1514484112

Table S3.

IntPath pathway analysis of genes associated with top 300 LMP2A-repressed sites (GFPCD19/LMP2ACD19 ≥ 1.5-fold) based on histone mark ChIP-seq signals

Histone mark Associated pathway P value
H3K4me1 Glycosaminoglycan biosynthesis - chondroitin sulfate 0.006109
p53 signaling pathway 0.006682
Apoptosis 0.008195
ES cell pluripotency pathways 0.014606
NLR proteins 0.017381
Pathways in cancer 0.024661
Adipogenesis 0.028524
Wnt signaling pathway and pluripotency 0.028527
Toll-like receptor signaling pathway 0.030697
Biotin metabolism 0.034783
Intestinal immune network for IgA production 0.037504
Glycan biosynthesis 0.037854
B-cell receptor signaling 0.043578
TGF-β receptor signaling pathway 0.047006
H3K4me3 Formaldehyde oxidation 0.008229
Pentose phosphate 0.012
Protein processing in endoplasmic reticulum 0.028723
Biotin metabolism 0.036036
Pyridoxal 5′-phosphate salvage pathway 0.036036
H3K27ac Pyridoxal 5′-phosphate salvage pathway 0.000317
TNF-α NF-κB signaling pathway 0.001924
Vitamin B6 metabolism 0.006169
Vasopressin-regulated water reabsorption 0.006324
Toll-like receptor signaling 0.020474
Interleukin signaling pathway 0.020788
Prostate cancer 0.020813
Phosphatidylethanolamine biosynthesis 0.021371
Kennedy pathway 0.024978
Pyrimidine ribonucleotides de novo biosynthesis 0.02844
Pyrimidine metabolism 0.029214
Aminoacyl-tRNA biosynthesis 0.036095
Integrin-mediated cell adhesion 0.036235
Glyoxylate and dicarboxylate metabolism 0.03643
Proteasome 0.037004
Hypertrophy model 0.048478

NLR, nucleotide-binding domain and leucine-rich repeat containing.