Table 2.
Characteristics statistically significantly associated with poor medication adherence (“low” MAQ classification)
| Variables | Univariate model
|
Multivariate model
|
|||||
|---|---|---|---|---|---|---|---|
| Low MAQ
|
Medium + high MAQ
|
P-value | aOR | 95% CI | P-value | ||
| n (%) | n (%) | ||||||
| Sex | |||||||
| Male | 547 (52.6) | 492 (47.4) | 0.5654 | ||||
| Female | 307 (54.1) | 260 (45.9) | |||||
| Age | |||||||
| <40 years | 587 (56.5) | 452 (43.5) | 0.0003 | 1.566 | 1.313 | 1.869 | 0.0002 |
| ≥40 years | 264 (47.1) | 296 (52.9) | |||||
| No | 761 (54.7) | 629 (45.3) | |||||
| Disease severity | |||||||
| CGI-S ≥4 | 785 (55.8) | 623 (44.2) | <0.0001 | 1.986 | 1.518 | 2.598 | <0.0001 |
| CGI-S, 4 | 69 (35.8) | 124 (64.2) | |||||
| Psychotic disorder | |||||||
| Schizophrenia | 555 (56.3) | 431 (43.7) | 0.0083 | ||||
| Schizoaffective disorder | 165 (52.2) | 151 (47.8) | |||||
| Persistent delusions | 71 (45.8) | 84 (54.2) | |||||
| Acute psychotic episode | 47 (44.8) | 58 (55.2) | |||||
| Other | 15 (38.5) | 24 (61.5) | |||||
| Insight | |||||||
| PANSS-G12 ≥4 | 572 (57.8) | 417 (42.2) | <0.0001 | 1.459 | 1.225 | 1.738 | 0.0003 |
| PANSS-G12 <4 | 279 (46.2) | 325 (53.8) | |||||
Abbreviations: MAQ, Medication Adherence Questionnaire; CGI-S, Clinical Global Impression Scale-Severity; PANSS-G12, Positive and Negative Syndrome Scale (lack of judgment and insight); aOR, adjusted odds ratio; CI, confidence interval.