Table 2. Genetic basis of intramedullary spinal cord tumors.
Genetic disorder | Associated tumor |
---|---|
Neurofibromatosis-1 | Acute nonlymphocytic leukemias Astrocytomas Carcinoid tumors Hematomas Hypothalamic gliomas Malignant nerve sheath tumors Meningiomas Neurofibromas Optic nerve gliomas Pheochromocytomas Primitive neuroectodermal tumors Rhabdomyosarcomas Wilms tumor |
Neurofibromatosis-2 | Bilateral acoustic schwannomas Ependymomas Gliomas Meningiomas Schwannomas |
Von Hippel-Landau | Adrenal pheochromocytomas Central nervous system hemangioblastoma (medulla oblongata or spinal cord) Epididymal cystadenomas Lindau tumor (cerebellum hemangioblastoma) Nephritic cysts Pancreatic cysts Renal cell carcinomas Renal cysts Retinal hemangioblastomas |