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. Author manuscript; available in PMC: 2016 Sep 15.
Published in final edited form as: Methods. 2015 May 29;86:80–88. doi: 10.1016/j.ymeth.2015.05.022

Table 1.

File formats used in ChIP-seq analysis.

File Type Brief Description Use in Analysis
FASTQ Illumina sequencing file
from experimental run
Raw ChIP-seq Data

FASTQC Illumina quality control file
for each Illumina
sequencing run
Evaluating ChIP-seq
Sequencing Data

SAM Alignment file from
Bowtie2 or BWA
Aligned ChIP-seq File

BAM Binary SAM file Aligned ChIP-seq File

wiggle (WIG) File containing results of
enumerating read hits at
each base location
Visualization File

ELAND Another alignment file
format, used as input in
MOSAiCS
For Peak Calling