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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Thromb Res. 2015 Aug 28;136(4):781–785. doi: 10.1016/j.thromres.2015.08.013

Table 3.

Hazard Ratios (HRs) and 95% CI of Venous Thromboembolism (VTE) in Relation to Dichotomized D-dimer and Thrombophilia SNPs, ARIC, 1993-2011.

Factor V Leiden, No
 Factor V Leiden, Yes
Low D-dimer* High D-dimer* Low D-dimer* High D-dimer*
 HR† of
VTE		 1 1.8 2.0 4.3
 [95% CI] -- [1.5, 2.1] [1.2, 3.5] [2.9, 6.2]
  n VTEs 212 245 14 30
O-Blood Type
 Non-O Blood Type
Low D-dimer* High D-dimer* Low D-dimer* High D-dimer*
 HR† of
VTE		 1 1.7 1.4 2.6
 [95% CI] -- [1.3, 2.4] [1.1, 1.9] [2.6, 3.4]
  n VTEs 79 93 146 175
*

Low D-dimer is lowest three quintiles (≤ 0.32 μg/mL) and high D-dimer is highest two quintiles (>0.32 μg/mL).

†

HR adjusted for sex, race, and age.