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. 2015 Feb 6;17(5):850–853. doi: 10.4103/1008-682X.142134

Figure 4.

Figure 4

Western blotting was used to detect the caspase cascade and Akt pathway-related protein with tetrandrine (TET) treatment in PC-3 and DU145 cells. Activation of caspase-3 and poly (ADP-ribose) polymerase, downregulation of phospho-Akt and Bcl-2, and upregulation of Bax were observed with 48 h treatment of TET. Glyceraldehyde-3-phosphate dehydrogenase was used as a loading control.