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ALVAC-HIV ± Remune does not affect the size of the viral reservoir from week 0 to week 24. Changes in the size of the viral reservoir from week 0 to week 24 were assessed by quantifying replication-competent virus using an ultrasensitive viral outgrowth assay. The number of IUPM PBMC was calculated from the pattern of positive wells by the method of maximum likelihood: (A) group 1: ALVAC-HIV + Remune; (B) group 2: ALVAC-HIV alone; (C) group 3: both placebos.
