Specific points of interest can be marked in the ultrasound image by the interventionalist that will automatically appear on the fluoroscopic image. In this case of a MitraClip® procedure, the echocardiographer displays the mitral valve with Color Doppler in the X-plane mode in order to define the most regurgitant jet (right upper panel). The interventionalist can then steer particular markers using the table-side control mouse, and place them to define the region of interest for the MitraClip® procedure. After adjusting the marker, it will appear on the fluoroscopic image, representing the exact region of interest, where the MitraClip® should be implanted (right lower panel).