Table 3. Summary of Studies About the Changes of Body Mass Index Standard Deviation Score During Gonadotropin-Releasing Hormone Agonist Therapy in Girls a.
Author (year), Reference | No | Treatment BMI-SDS for CA | |||
---|---|---|---|---|---|
Baseline | Duration of Therapy, Mo | Final Visit | P Value | ||
Current study | |||||
Intervention group | 46 | 0.84 ± 1.01 | 0.92 ± 0.82 (12 mo) | ___ | NS |
Control group | 64 | 1.49 ± 1.28 | 1.49 ± 1.16 (12 mo) | ___ | NS |
Arrigo (2004) | |||||
Intervention group | 101 | 1.39 ± 1.07 | 0.61 ± 0.79 (12 mo) | 0.11 ± 0.52 | < 0.001 |
Control group | No control group | ||||
Yuan (2011) | |||||
Intervention group | 57 | 0.35 ± 0.79 | 0.49 ± 0.72 (12 mo) | -0.12 ± 0.58 | 0.03 |
Control group | 77 | 0.39 ± 0.89 | ___ | 0.29 ± 0.94 | NA |
Lee (2012) | |||||
Intervention group | 38 | 0.58 ± 1.18 | 0.79 ± 0.84 (12 mo) | 0.96 ± 0.83 | < 0.05 |
Control group | No control group | ||||
Traggiai (2005) | |||||
Intervention group | 29 | 1.7 | 1.8 (12 mo) | 1.6 | NR |
Control group | 45 | 2.1 | 1.6 (12 mo) | 1 | NR |
Poomthavorn (2011) | |||||
Intervention group | 47 | 1.26 ± 0.95 | NR | 0.16 ± 1 | NA |
Control group | 11 | NA | |||
Oostdijk (1996) | |||||
Intervention group | 30 | 1.7 | 1.824 mo | 1.44 | NS |
Control group | No control group | ||||
Palmert (1999) | |||||
Intervention group | 96 | 1.1 ± 0.1 | 0.9 ± 0.136 mo | 0.9 ± 0.1 | NS |
Control group | No control group |
a Abbreviations: BMI-SDS for CA, body mass index standard deviation score for chronological age; NA, not available; NS, not significant.