Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Sep 21;212(10):1623–1640. doi: 10.1084/jem.20142088

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 Sekiya et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 9. — Nr4a-TKO T reg cells induce GC reactions. (A) Total IgE and IgG1 levels in recipient CD3ε-deficient mice transferred with no cells, Ly5.2⁺WT T reg cells (4 × 10⁵), or Ly5.2⁺Nr4a-TKO T reg cells (4 × 10⁵), with or without Ly5.1⁺ WT T reg cells (2 × 10⁵). Each symbol represents an individual mouse; small horizontal lines indicate the mean. (B) Flow cytometry profiles of B220⁺ spleen cells from A. Numbers adjacent to outlined areas indicate the percentage of cells in each. (C) Quantification of results in B. Frequencies of GL-7⁺Fas⁺ GC B cells among B220⁺ cells are shown (n = 5 mice per group, pooled from 2 independent experiments). (D) PAS staining of mucus-producing cells (pink) in the lungs of CD3ε-deficient mice from A. Outlined area is enlarged below. Bars, 100 µm. Error bars in C denote mean ± SD. *, P < 0.05; **, P < 0.01; ***, P < 0.005; ****, P < 0.001 (one-way ANOVA with Bonferroni test).