Figure 5.
Pancreatic macrophages in early postnatal life. Islets and stromal macrophages from 1-, 2-, and 4-wk-old mice (gated on live singlets for CD45+) were evaluated for expression of F4/80, CD11b, CD11c, MHC-II, Ly6C, CD206, and CD301. Islet macrophages were gated from all CD45+ islet cells, whereas pancreatic stroma macrophages were gated on F4/80+ CD11b+ profile (indicated by arrows). Data are representative of two independent experiments at 1 wk and three independent experiments at 2 and 4 wk, each having four to eight mice per time point.