FIG 1.
Size comparison of GFP with viral proteins illustrates the potential effect of steric hindrance. (A) Size comparison of GFP (PDB code 2B3P), the coat protein of tobacco mosaic virus (2OM3), and 1918 influenza virus hemagglutinin membrane glycoprotein (1RUZ) relative to 5-nm scale bar. (B) Hypothetical fusion protein of a major capsid protein, Vp54 of paramecium bursaria chlorella virus type 1 (1M4X), with GFP. The trimeric capsomer and associated GFP molecules represent the potential restrictions of a viral FP fusion protein.