FIG 2.

Inhibition of virion maturation underlies ALLINI potency. (A) (Left) Quantitation of core morphotype frequencies (average ± SD for two independent experiments) for sets of 100 counted HIV-Luc particles; (right) representative TEM images of mature, eccentric, and immature virions produced in these experiments. (B) Quantitation of late reverse transcription (LRT) product formation from infections initiated with samples shown in panel A. (C) Antiviral activity as assessed by bulk luciferase output. Error bars in panels B and C represent the variations obtained from three independent experiments.