FIG 5.

Tomo-bubblegrams of HIV-1 particles. (A to X) Each pair of panels shows a central section from an initial tomogram (left) and the corresponding section from the tomo-bubblegram (right). The types of virions analyzed are indicated on the left of each block. BIB-2 (10×) and BI-D (10× EC₅₀ for panels G, I, and L; 100× EC₅₀ for panels H, J, and K) were used at full inhibitory concentrations. Particles with conical cores are framed in red, and those with nonconical cores are framed in blue; particles lacking eccentric condensates are framed with continuous lines, and particles that have eccentric condensates are framed with dashed lines. Bar, 50 nm. Full tomograms of the virions in panels B (Movie S1), I (Movie S2), R (Movie S3), and X (Movie S4) are shown in the supplemental material.