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Type I IFN secreted from CD11c+ myeloid dendritic cells impairs MCMVr replication. MEF or IFNAR−/− MEF were infected with MCMVr at an MOI of 0.1 and cocultured in the absence or presence of CD11c+ mDC (ratio of 1:4). Supernatants were collected in triplicates at day 5, and titration was performed on MEF. Graphs show average values ± SEM from three independent experiments.
