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Representation of the experimental scheme. Different progenies of the first generation (F1a, F1b, and F1c) were obtained from 37 goats orally inoculated with scrapie ovine brain homogenate (F0). Subsequently, a second generation of progeny (F2a) was produced from F1a and F1b progenies. All goats were kept in the same environment. The period of occurrence of scrapie in F0 and F1b groups is indicated as months p.i. or months of age of the affected animals.
