FIG 3.
Comparison of goats survivorship by susceptibility status. Goat genotypes were used to categorize goats into three susceptibility levels: resistant (D145D, Q222K, and Q222K-S240P), susceptible with long postinfection time (R/H154H, R154H-S240P, P168Q-P240P, R211Q, and R211Q-S240P), and susceptible with short postinfection time (wild-type, G37V, Q168Q-P240P, and S/P240P). The log rank test was used to compare the three survival curves. Hash marks are used to indicate censoring. (A) Kaplan-Meier survival curves of 37 goats (F0) orally infected with ovine scrapie. Thirteen animals not diagnosed as scrapie cases were included in the analyses as censored at death. (B) Kaplan-Meier survival curves of 20 offspring goats belonging to the F1b group. Nine animals not diagnosed as scrapie cases were included in the analyses as censored at death.