TABLE 1.

PRNP genotype, postinfection time, clinical status, and PrP^Sc detection in goats orally infected with an ovine scrapie brain homogenate^a

Goat	Genotype	Clinical signs	Incubation time (days)	PrPSc detection
				Obex	LT
0931	WT	Yes	700	Pos	Pos
0937	WT	Yes	613	Pos	Pos
0947	WT	Yes	779	Pos	Pos
0948	WT	Yes	738	Pos	Pos
0932	WT	Yes	681	Pos	Pos
0946	G37V	Yes	766	Pos	Pos
0941	G37V	Yes	723	Pos	Pos
0903	G37V	Yes	688	Pos	Pos
0908	G37V-Q222K	No	1,961	Neg	Neg
0951	D145D	No	1,913	Neg	Neg
0955	D145D	No	1,913	Neg	Neg
0921	H154H	Yes	1,184	Pos	Pos
0911	R154H	Yes	1,101	Pos	Pos
0926	R154H	Yes	955	Pos	Pos
0902	R154H-S240P	Yes	1,030	Pos	Pos
0904	R154H-S240P	Yes	898	Pos	Pos
0935	P168Q-P240P	Yes	1,184	Pos	Pos
0927	Q168Q-P240P	Yes	672	Pos	Pos
0924	R211Q	Yes	2,109	Pos	Pos
0919	R211Q-S240P	Yes	1,347	Pos	Pos
0928	R211Q-S240P	Yes	1,712	Pos	Pos
0950	Q222K	No	2,067	Neg	Neg
0923	Q222K-S240P	No	1,848	Neg	Neg
0944	S240P	Yes	743	Pos	Pos
0953	P240P	Yes	778	Pos	Pos
0922	P240P	Yes	711	Pos	Pos

^aPrP^Sc was detected via immunohistochemical and Western blotting techniques. LT, lymphoid tissue; Pos, positive; Neg, negative; WT, wild type.