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EGCG and delphinidin induce HCVpp deformation. HCVpp of genotype 2a, NoEnvpp, and VSV-Gpp were incubated for 1 h at 37°C in the presence of 50 μM EGCG, delphinidin, or petunidin and processed for cryo-TEM. Cryo-TEM images representative of HCVpp, NoEnvpp, and VSV-Gpp treated with EGCG, delphinidin, and petunidin are presented. The arrows indicate membrane deformations on HCVpp incubated with EGCG or delphinidin. Bars, 50 nm.
