FIG 3.
Predicted genome structures and features in the ORF30 region for parental and mutant viruses. (A) VZVLUC parental virus with shared coding regions for ORFs 30 and 31. The ORF31 promoter is predicted to fall within the 5′ coding sequence of the 2,310-bp ORF30 gene. (B) Δ30L (large ORF30 deletion) has an internal deletion of 1,918 bp. (C) Δ30M (medium ORF30 deletion) has an internal deletion of 1,337 bp. (D) Δ30S (small ORF30 deletion) has an internal deletion of 179 bp. (E to G) ORF30 sequences containing specific alanine substitutions in conserved terminase region IX. (H) ORF30 sequence containing three alanine substitutions in conserved terminase region IV, containing a putative zinc finger. The amino acid numbers are listed along with the amino acid changes. Promoters are indicated with arrows (galK promoter; for E. coli galactokinase).