Table IV.

NIHSS scores and inflammatory indicators before and after treatment.

Indicators	Successful thrombolysis (n=36)	Failed thrombolysis (n=12)	ta	P-valuea	Control (n=14)	tb	P-valueb
NIHSS score
On admission	10.0±4.8	10.8±5.0	0.495	0.623	9.8±4.5	0.135	0.893
Post-stroke day 1	4.0±2.2	8.7±3.4	5.274	<0.001	9.0±3.2	6.323	<0.001
Post-stroke day 7	2.2±1.6	6.0±2.4	6.252	<0.001	7.0±2.1	8.710	<0.001
Body temperature (°C)
On admission	36.4±0.5	36.5±0.4	0.628	0.533	36.6±0.5	1.270	0.210
Post-stroke day 1	36.5±0.5	36.7±0.6	1.141	0.260	36.6±0.5	0.635	0.528
Post-stroke day 3	36.5±0.7	37.3±0.9	3.189	0.003	37.4±0.9	3.763	<0.001
Post-stroke day 5	36.7±0.6	36.8±0.5	0.519	0.606	36.9±0.6	1.058	0.295
Post-stroke day 7	36.5±0.6	36.6±0.6	0.500	0.619	36.5±0.5	0.553	0.583
Leukocyte (109/l)
On admission	8.8±1.4	8.7±2.0	0.192	0.849	9.0±1.9	0.406	0.687
Post-stroke day 1	10.9±1.8	11.2±2.3	0.466	0.643	11.0±2.0	0.171	0.865
Post-stroke day 3	9.0±2.0	12.6±2.5	5.070	<0.001	12.5±2.6	5.100	<0.001
Post-stroke day 5	8.8±1.2	9.1±1.8	0.658	0.514	9.3±2.0	1.087	0.282
Post-stroke day 7	8.5±1.4	8.7±1.5	0.421	0.676	8.8±1.8	0.627	0.534
hs-CRP (mg/l)
On admission	9.0±6.4	8.1±6.6	0.419	0.677	7.9±7.0	0.532	0.597
Post-stroke day 1	10.1±7.4	14.3±8.7	1.630	0.110	12.3±7.0	0.958	0.343
Post-stroke day 3	32.8±9.9	74.6±13.1	11.663	<0.001	80.4±11.6	14.548	<0.001
Post-stroke day 5	28.0±8.4	50.8±10.6	7.621	<0.001	52.7±10.0	8.849	<0.001
Post-stroke day 7	23.5±7.6	27.6±9.8	1.504	0.139	28.2±8.8	1.879	0.066

^aComparison between the successful thrombolysis and failed thrombolysis groups

^bComparison between the successful thrombolysis and control groups. Successful thrombolysis group, after thrombolytic therapy, the reduction of NIHSS score within 24 h was ≥4; failed thrombolysis group, after thrombolytic therapy, the reduction of NIHSS score within 24 h was <4; control group, no thrombolysis was performed and only conventional therapy was applied. NIHSS, National Institutes of Health Stroke Scale; hs-CRP, high-reactivity C-reactive protein.