Table V.
Baseline characteristics and respiratory variables during the SBT in the validation cohort (n=530).
| Parameter | Extubation faliure (n=90) | Extubation success (n=440) | P-value | |
|---|---|---|---|---|
| Age (years) | 69 (65.74) | 67 (59.72) | 0.04 | |
| APACHE II score | 21.4±5.4 | 21.5±4.8 | 0.447 | |
| MBP (mmHg) | 88.6±9.3 | 89.8±8.7 | 0.17 | |
| HR (beats/min) | 86.6±15.7 | 82.8±15.8 | 0.035 | |
| Duration of MV (days) | 9 (7,12.3) | 8 (6,11) | 0.05 | |
| 1 min of SBT | ||||
| RSBI1 (breaths/min/l) | 91±32 | 75±36 | <0.001 | |
| P0.1 × RSBI1 (cmH2O·breaths/min/l) | 336±160 | 217±145 | <0.001 | |
| 30 min of SBT | ||||
| RSBI30 (breaths/min/l) | 107±36 | 69±31 | <0.001 | |
| P0.1 × RSBI30 (cmH2O·breaths/min/l) | 443±163 | 218±132 | <0.001 | |
| ∆RSBI30 (%) | 125±59 | 99±36 | <0.001 | |
| 60 min of SBT | ||||
| RSBI60 (breaths/min/l) | 104±57 | 67±34 | <0.001 | |
| P0.1 × RSBI60 (cmH2O·breaths/min/l) | 420±251 | 211±133 | <0.001 |
Data expressed as the mean ± standard deviation or as the median (interquartile range) if the data were not normally distributed. SBT, spontaneous breathing trial; APACHE II, acute physiology and chronic health evaluation; MBP, mean blood pressure; HR, heart rate; P0.1, airway occlusion pressure; P0.1 × RSBI, product of airway occlusion pressure and RSBI; RSBIn, rapid shallow breathing index at n min;∆RSBI30, change in RSBI at 30 min of SBT, expressed as a percentage of RSBI30 to RSBI1.