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. 2015 Aug 27;30(5):648–656. doi: 10.3904/kjim.2015.30.5.648

Table 1.

Summary of patients' information collected during a severe hypoglycemic event

Variable Total Hypokalemia Normokalemia Hyperkalemia p value
No. of individuals 219 48 167 4
Age, yr 71.0 ± 10.7 69.4 ± 11.1 71.4 ± 10.6 71.3 ± 11.8 0.13
Sex, male:female 90:129 20:28 69:98 1:3 0.97
Duration of diabetes, yr 10 (0.08–40.0) 10 (0.083–40.0) 10 (0.16–40) 10 (3–20) 0.06
Hypertension 145 (66.2) 34 (70.8) 108 (64.7) 3 (75.0) 0.43
 Duration, yr 7 (0.33–40) 10 (0.33–40) 10 (1–40) 8 (8–10) 0.87
 ARB/ACE inhibitors 50 11 39 0 0.49
 Diuretics 22 5 17 0 0.80
 β-Blockers 13 6 6 1 0.07
 Calcium channel blockers 36 10 25 1 0.69
Treatment of diabetes 214 47 163 4 0.57
 OHA alone 169 (79.0) 35 (74.5) 131 (80.4) 3 (75.0)
 Insulin alone 26 (12.1) 6 (12.8) 19 (11.7) 1 (25.0)
 Combination 19 (8.9) 6 (12.8) 13 (8.0) 0
HbA1c, % 6.6 ± 1.7 6.9 ± 1.9 6.5 ± 1.7 5.7 ± 0.0 0.49
Blood glucose, mg/dL 34 (6–69) 30 (14–62) 35 (10–69) 46 (6–65) 0.04
Serum sodium, mmol/L 141.5 ± 4.8 141.8 ± 3.7 141.4 ± 5.1 139.2 ± 3.9 0.78
Serum chloride, mmol/L 103.5 ± 5.1 102.6 ± 4.7 103.8 ± 5.3 102.6 ± 3.8 0.12
Serum potassium, mmol/L 4.0 ± 0.6 3.2 ± 0.2 4.1 ± 0.4 5.7 ± 0.2 < 0.01

Values are presented as number, mean ± SD, median (interquartile range), or number (%). A p value indicates comparison of participant characteristics between hypokalemia and normokalemia groups. Vital signs and laboratory data during severe hypoglycemia were measured upon hospital arrival.

ARB, angiotensin II receptor blockers; ACE, angiotensin-converting enzyme; OHA, oral hypoglycemic agent; HbA1c, hemoglobin A1c.