Table V.
Correlation between genetic polymorphisms of GSTP1 and susceptibility to lung cancer and histology of lung cancer.
| Genotypes of GSTP1, n (%) | ||||||
|---|---|---|---|---|---|---|
| Group | n | A/A | Non-A/A | ORa | 95% CI | P-value |
| Control | 152 | 86 (56.6) | 66 (43.4) | 1.00 | ||
| Lung cancer | 150 | 74 (49.3) | 76 (50.7) | 1.43 | 0.890–2.306 | 0.138 |
| SQ | 70 | 27 (38.6) | 43 (61.4) | 2.31 | 1.180–4.512 | 0.015 |
| AD | 61 | 34 (55.7) | 27 (44.3) | 1.12 | 0.579–2.180 | 0.730 |
| Others | 19 | 9 (47.4) | 10 (52.6) | 1.71 | 0.636–4.617 | 0.286 |
a
adjusted by gender, age and smoking status. GSTP1, glutathione S-transferase π 1; OR, odds ratio; CI, confidence interval; SQ, squamous cell carcinoma; AD, adenocarcinoma.