Figure 1.
Transforming growth factor-β (TGF-β)-activated kinase 1 (TAK1) inhibitor (5Z)-7-oxozeaenol downregulates Baculoviral inhibitor of apoptosis (IAP) repeat containing (BIRC)3 in distal oesophageal adenocarcinoma cells. (A) Western blot analysis of BIRC3 basal expression in FLO-1 and KYAE-1 distal oesophageal adenocarcinoma cells compared with AsPC-1 and AsPC-1shTAK1 pancreatic cancer cells as positive and negative control, respectively. (B and C) Western blot analysis of BIRC3 levels after 24 h of treatment with increasing doses of (5Z)-7-oxozeaenol. γ-Tubulin was detected as a loading control.