Table 2. Relationship between ADAM10 protein expression and variables of tumour progression.
| Tumour characteristic | N | Median ADAM10 protein levels (ng mg−1) | P-valuea |
|---|---|---|---|
|
Age (years) | |||
| ⩽50 | 40 | 1.73 | 0.018 |
| >50 | 77 | 1.08 | |
|
Tumour size (cm) | |||
| ⩽2 | 32 | 1.07 | 0.315 |
| >2 | 76 | 1.20 | |
|
Grade | |||
| 1 and 2 | 46 | 0.84 | <0.001 |
| 3 | 60 | 1.74 | |
|
Nodal status | |||
| 0 | 56 | 1.64 | 0.146b |
| 1–3 | 30 | 0.84 | |
| 4–9 | 15 | 1.08 | |
| >10 | 9 | 1.13 | |
|
ER status | |||
| Negative | 38 | 1.79 | 0.005 |
| Positive | 79 | 1.08 | |
|
HER2 status | |||
| Negative | 100 | 1.08 | 0.452 |
| Positive | 6 | 1.54 | |
|
Histological type | |||
| Ductal (D) | 92 | 1.18 | 0.496b |
| Lobular (L) | 16 | 1.02 | |
| D and L | 5 | 1.03 | |
Abbreviation: ER, oestrogen receptor.
a
Data were analysed using the Mann–Whitney U-test.
b
Data were analysed using Kruskal–Wallis analysis.