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Kaplan-Meier curves of OS and RFS (A) for patients with proximal colon cancer, according to APC mutation and microsatellite instability status (discovery cohort), and (B) for patients with proximal colon cancer, according to APC gene signature and microsatellite instability status (validation cohort, GSE39582 (Marisa et al, 2013)). Abbreviations: MSS/MSI, microsatellite stable/unstable.
