Figure 4.

PDTC abrogated upregulation of p65 expression in response to syn-hsa-miR-181b transfection. p65 expression was significantly increased following transfection with syn-has-miR-181b, while the negative control group had little effect on p65 expression. (A) Representative image of western blotting from three repeated experiments, and (B) relative protein expression levels of p65, as determined using ImageJ software. **P<0.01 vs. negative control group. PDTC can abrogate the upregulation of p65 expression. ^##P<0.01, vs. 100 µM PDTC group. Representative images were acquired from three different experiments. LPS, lipopolysaccharide; PDTC, ammonium pyrrolidinedithiocarbamate.