Figure 5.

Effect of EESB on the activation of caspase-9/caspase-3. Cells were treated with the indicated concentration of EESB for 1 h, followed by stimulation with 10 ng/ml IL-6 for 24 h. (A) Caspase-9 and (B) caspase-3 activities were determined using a colorimetric assay. Data were normalized to the caspase activities within control cells and represented as the fold of control. *P<0.05 vs. control cells; ^#P<0.05 vs. cells treated with IL-6 but not EESB. EESB, ethanol extract of Scutellaria barbata D. Don; IL-6, interleukin-6.