Table IV.

Comparison of liver function between immunotherapy and control groups.

Serum parameter	Control group (n=15)	Immunotherapy group (n=14)	P-value
ALT (µ/l)
Pre-immunotherapy	41.3±7.8	42.8±7.5	0.598
Post-immunotherapy	37.5±6.3	37.9±6.2	0.866
D-value of pre and post-immunotherapy	−3.7±7.2	−4.9±5.2	0.632
AST (µ/l)
Pre-immunotherapy	46.1±7.2	46.4±7.9	0.252
Post-immunotherapy	35.8±6.5	37.7±5.3	0.268
D-value of pre and post-immunotherapy	−10.7±8.8	−8.7±5.6	0.556
Albumin (g/l)
Pre-immunotherapy	39.27±4.89	41.31±3.24	0.200
Post-immunotherapy	38.43±5.98	44.39±3.87	0.004
D-value of pre and post-immunotherapy	−0.84±4.63	3.07±2.29	0.008
ChE (µ/l)
Pre-immunotherapy	5503.49±1246.45	6043.28±1785.90	0.351
Post-immunotherapy	5701.98±1303.10	6679.91±1480.46	0.069
D-value of pre and post-immunotherapy	198.49±562.76	636.63±510.47	0.037

D-value is the difference between the liver function index pre- and post-immunotherapy. ALT, alanine aminotransferase; AST, aspartate aminotransferase; ChE, cholinesterase.