Table V.
Parameter | After first immunotherapy (n=14) | After third immunotherapy (n=14) | P-value |
---|---|---|---|
Cell count pre-culture | |||
PBMC (x107/l) | 8.93±4.07 | 7.32±2.96 | 0.996 |
Cell count post-culture | |||
MDC (x107/l) | 10.74±5.26 | 16.5±9.16 | 0.052 |
CIK (x1010/l) | 2.65±2.29 | 3.23±1.46 | 0.424 |
T cell subgroup ratio post-culture (%) | |||
CD83+ | 50.60±28.65 | 74.87±20.87 | 0.004 |
CD86+ | 62.69±29.50 | 86.71±12.77 | 0.011 |
CD3+CD8+ | 68.70±15.73 | 81.80±9.26 | 0.000 |
CD3+CD56+ | 29.59±11.42 | 35.82±8.92 | 0.058 |
PBMC, peripheral blood mononuclear cell; MDC, myeloid dendritic cell; CIK, cytokine-induced killer.