Table 1.
Baseline demographic and clinical characteristics
| Baseline value in all patients (n=330) | ||
|---|---|---|
| Age (years) | 64·4 (11·7), n=315 | |
| Sex | ||
| Women | 150/330 (45%) | |
| Men | 180/330 (55%) | |
| Forced vital capacity (%) | 62% (22·6), n=258 | |
| % Weight loss from diagnosis to baseline (kg) | 8·6 (9·8), n=252 | |
| ALSFRS-R score | 28 (8·5), n=307 | |
| Body-mass index (kg/m2) | 23·3 (4·4), n=274 | |
| Monthly ALSFRS-R decline | 2·2% (1·7%), n=290 | |
| Disease duration from diagnosis (months) | 16·7 (5·8–14·9), n=309 | |
| Non-invasive ventilation routine users | 81/323 (25%) | |
| Site of disease onset | ||
| Limb | 152/324 (47%) | |
| Bulbar | 165/324 (51%) | |
| Both limb and bulbar | 6/324 (2%) | |
| Respiratory | 1/324 (0·3%) | |
Data are mean (SD), median (IQR), or n/N (%). ALSFRS-R=amyotrophic lateral sclerosis functional rating scale revised.