Table 2.
Baseline differences of patients who underwent PEG, RIG, or PIG
| PEG | RIG | PIG | Statistic (n) | p value | ||
|---|---|---|---|---|---|---|
| Age (years) | 64·2 (11·7), n=157 | 63·6 (9·8), n=114 | 67·2 (12·6), n=41 | F (312) | 0·200 | |
| Sex | χ2 (327) | 0·683 | ||||
| Women | 73/163 (45%) | 59/121 (49%) | 18/43 (42%) | |||
| Men | 90/163 (55%) | 62/121 (51%) | 25/43 (58%) | |||
| FVC (%) | 65·4 (22·2), n=136 | 59 (23·1), n=87 | 52 (19·7), n=33 | F (256) | 0·004 | |
| % Weight loss from diagnosis to baseline (kg) | 7·1 (8·5), n=117 | 8·7 (9·9), n=98 | 13 (12·3), n=35 | F (250) | 0·008 | |
| ALSFRS-R score | 29·1 (8·2), n=152 | 27·7 (8·8), n=114 | 24·7 (7·9), n=39 | F (305) | 0·014 | |
| Body-mass index (kg/m2) | 23·7 (4), n=135 | 23·4 (5·1), n=102 | 21·8 (3), n=34 | F (271) | 0·091 | |
| Monthly ALSFRS-R decline | 2·1% (1·5), n=144 | 2·4% (2·1), n=105 | 2·1% (1·2), n=39 | F (288) | 0·302 | |
| NIV routine users | 29/162 (18%) | 23/118 (19%) | 28/42 (67%) | χ2 (322) | 0·001 | |
| Site of disease onset | χ2 (321) | 0·369 | ||||
| Limb | 74/161 (46%) | 54/117 (46%) | 23/43 (53%) | |||
| Bulbar | 86/161 (53%) | 59/117 (50%) | 18/43 (42%) | |||
| Both limb and bulbar | 1/161 (1%) | 3/117 (3%) | 2/43 (5%) | |||
| Respiratory | 0/161 | 1/117 (1%) | 0/43 | |||
Data are mean (SD) or n/N (%). PEG=percutaneous endoscopic gastrostomy. RIG=radiologically inserted gastrostomy. PIG=per-oral image-guided gastrostomy. F=one-way ANOVA F test. FVC=forced vital capacity. ALSFRS-R=amyotrophic lateral sclerosis functional rating scale revised. NIV=non-invasive ventilation.