Table 10.
miRNA deregulated by integration miRNA and mRNA
Biomarker | Biological effect | References |
---|---|---|
miR-16, 155, 125b, 374a | predictive of overall survival (P = 0.05) | [307] |
miR-16, 125b, 374a, 374b, 421, 655, 497 | predictive of distant-disease free survival (P = 0.009) | [307] |
miR-1307, 103, 328, 83, 874, 484, 148b | associated with overall survival across different clinical and molecular subclasses | [308] |
miR-767-3p, 128a, 769–3, 135a, and miR-27b, 144, 210, 42, 150, 30c | associated with DRFS in estrogen receptor | [309] |
miR-335, 337-5p, 451, 486-3p, 520a-5p, 548d-5p, 15a, 24, 29a, 30b, 320, 342-5p, 342-3p | associated with inflammatory breast cancer | [310] |
miR-150, 155, 142 | have strong positive correlation to the immune response module | [311] |
miR-130b, 19a, 449a, 299, 154, 145 | association with proliferation | [311] |
miR-29c | associated with cell adhesion/extra cellular matrix | [311] |
miR-125b, miR-182 and miR-183 | highly overexpressed in ductal carcinoma in situ | [312] |
miR-200c, miR-205, and miR-375 | down-regulated miRNAs in invasive cell lines | [313] |