Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Effects of intrathecal fentanyl blockade on breathing frequency and V̇E/V̇CO2 in COPD patients cycling at 80 W (80% of max). Fentanyl block resulted in a reduced fR and V̇E/V̇CO2 which persisted throughout the exercise. Vd/VT during exercise was also reduced with fentanyl (not shown). Dyspnoeic sensations were reduced and exercise time prolonged as V̇E and expiratory flow limitation were reduced with fentanyl blockade. Data from Gagnon et al. [45].
