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Particle size and release profile parameters of different surfactant formulations
| Surfactant/stabilizer | Tween 80 | Tween 80+ phosphatidylcholin | Pluronic F127+ phosphatidylcholin | Phosphatidylcholin | Pluronic F127 | PVA | PVP |
|---|---|---|---|---|---|---|---|
| Particle size (nm) | 83 | 91 | 169 | 203 | 210 | 265 | 306 |
| Burst release (%) | 27.5 | 17.13 | 8.4 | 11.8 | 11.6 | 10.5 | 6.4 |
| Release rate (%/h) | 1.49 | 1.55 | 1.49 | 1.63 | 1.4 | 1.16 | 1.12 |
| Max. drug depletion (%) | 86.42 | 84.14 | 81.68 | 72.21 | 78.44 | 66.14 | 46.8 |
