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. 2015 Aug 25;11:1486–1493. doi: 10.3762/bjoc.11.161

Table 2.

Scope of the tandem CEYM-IMDAR protocol.

graphic file with name Beilstein_J_Org_Chem-11-1486-i002.jpg

entry 1 (R) 2 3 (yield)a

1 1a (H) Inline graphic
2a
Inline graphic
3a (57%)
2 1a (H) Inline graphic
2b
Inline graphic
3b (38%)
3 1a (H) Inline graphic
2c
Inline graphic
3c (62%)
4 1b (F) Inline graphic
2c
Inline graphic
3d (45%)
5 1c (OMe) Inline graphic
2c
Inline graphic
3e (35%)
6 1a (H) Inline graphic
2d
Inline graphic
3f (50%)
7 1a (H) Inline graphic
2e
Inline graphic
3g (44%)

aIsolated yields after column chromatography. All final products 3 were obtained as single diastereoisomers.